FEDERICO BARONIO

Email: federico.baronio@aosp.bo.it

Genere: Male

1/2006 - 12/2008: Dottore di Ricerca (Ph.D.)

5/2001 - 10/2005: Specialista in Pediatria 

10/1991 - 10/1998: Dottore in Medicina e Chirurgia

• inglese (A1)

• Collaborazione alla realizzazione di una APP Medica "Smart Pediatric Endocrinology"

• ARFSAG AISLO
• Scuola di Perfezionamento in Endocrinologia e Diabetologia Pediatrica-SIEDP 2009
• ESPE Summer School - Nunspeet, The Netherlands 2006
• Frequenza ambulatorio e reparto di Malattie endocrino Metaboliche, Az Meyer-Firenze 1/3/2010-1/9/2010
• Socio Ordinario di Società italiana di Pediatria
• Socio Ordinario di Società Italiana di Endocrinologia e Diabetologia Pediatrica
• Socio Ordinario di European Society of Pediatric Endocrinology
• Partecipazione continuativa anche come relatore di comunicazioni orali o presentazione di Poster ai Congressi Nazionali SIEDP e ESPE dal 2004 e SSIEM dal 2010
• 1. Balsamo A, Cicognani A, Baldazzi L, Barbaro M, Baronio F, Gennari M, Bal M,Cassio A, Kontaxaki K, Cacciari E. CYP21 genotype, adult height, and pubertal development in 55 patients treated for 21-hydroxylase deficiency. J Clin Endocrinol Metab. 2003 Dec;88(12):5680-8. Erratum in: J Clin Endocrinol Metab. 2004 Nov;89(11):5409.2. Balsamo A, Antelli A, Baldazzi L, Baronio F , Lazareva D, Cassio A, and Cicognani AA new DAX1 gene mutation associated with congenital adrenal hypoplasia and hypogonadotropic hypogonadism Am J Med Genet 2005 135A:292¿2963. Longhi A, Pasini A, Cicognani A, Baronio F, Pellacani A, Baldini N and Bacci GHeight as a risk factor for osteosarcomaJ Pediatr Hematol Oncol. 2005 27:314¿3184. Balsamo A, Wasniewska M, Di Pasquale G, Salzano G, Baronio F, Bombaci S, De Luca FBirth length and weight in congenital adrenal hyperplasia according to the different phenotypesEur J Pediatr. 2006 Jun;165(6):380-3. Epub 2006 Mar 7
• 5. Zucchini S, Pirazzoli P, Baronio F, Gennari M, Bal MO, Balsamo A, Gualandi S, Cicognani A. Effect on adult height of pubertal growth hormone retesting and withdrawal of therapy in patients with previously diagnosed growth hormone deficiency. J Clin Endocrinol Metab. 2006 Nov;91(11):4271-6. Epub 2006 Aug 15. 6. Balsamo A, Cicognani A, Gennari M, Sippell WG, Menabo S, Baronio F, Riepe FG. Functional characterization of naturally occurring NR3C2 gene mutations in Italian patients suffering from pseudohypoaldosteronism type 1. Eur J Endocrinol. 2007 Feb;156(2):249-56.
• 7. Corrias A, Cassio A, Weber G, Mussa A, Wasniewska M, Rapa A, Gastaldi R, Einaudi S, Baronio F, Vigone MC, Messina MF, Bal M, Bona G, de Sanctis C; Study Group for Thyroid diseases of Italian Society for Pediatric Endocrinology and Diabetology (SIEDP/ISPED) Thyroid nodules and cancer in children and adolescents affected by autoimmune thyroiditis. Arch Pediatr Adolesc Med. 2008 Jun; 162(6): 526-31 8. Cassio A, Ricci G, Baronio F, Miniaci A, Bal M, Bigucci B, Conti V, Cicognani A. Long-term clinical significance of thyroid autoimmunity in children with celiac disease. J Pediatr. 2010 Feb;156(2):292-5. Epub 2009 Oct 20. 9. Corrias A, Mussa A, Baronio F, Arrigo T, Salerno M, Segni M, Vigone MC, Gastaldi R, Zirilli G, Tuli G, Beccaria L, Iughetti L, Einaudi S, Weber G, De Luca F, Cassio A; Study Group for Thyroid Diseases of Italian Society for Pediatric Endocrinology and Diabetology (SIEDP/ISPED). Diagnostic features of thyroid nodules in pediatrics. Arch Pediatr Adolesc Med. 2010 Aug;164(8):714-9
• 10. Baronio F, Battisti L, Radetti G. Central hypothyroidism following chemotherapy for acute lymphoblastic leukemia. J Pediatr Endocrinol Metab. 2011;24(11-12):903-6. 11. Masetti R, Biagi C, Kleinschmidt K, Prete A, Baronio F, Colecchia A, Festi D, Pession A. Focal nodular hyperplasia of the liver after intensive treatment for pediatric cancer: is hematopoietic stem cell transplantation a risk factor? Eur J Pediatr. 2011 Jun;170(6):807-12. Epub 2011 Jan 12 12. Betterle C, Ghizzoni L, Cassio A, Baronio F, Cervato S, Garelli S, Barbi E, Tonini G. Autoimmune-Polyendocrinopathy-Candidiasis-Ectodermal- Dystrophy (APECED) in Calabria: clinical, immunological and genetic patterns. J Endocrinol Invest. 2011 Nov 21. [Epub ahead of print] 13. Cassio A, Monti S, Rizzello A, Bettocchi I, Baronio F, D'Addabbo G, Bal MO, Balsamo A. Comparison between liquid and tablet formulations of levothyroxine in the initial treatment of congenital hypothyroidism. J Pediatr. 2013 Jun;162(6):1264-9, 1269.e1-2.
• 14. Maltoni G, Zucchini S, Scipione M, Rollo A, Balsamo C, Bertolini C, Baronio F, Rondelli R, Pession A. Severe hypoglycemic episodes: A persistent threat for children with Type 1 diabetes mellitus and their families. J Endocrinol Invest. 2013 Sep;36(8):617-621. 15. Catarzi S, Caciotti A, Thusberg J, Tonin R, Malvagia S, la Marca G, Pasquini E, Cavicchi C, Ferri L, Donati MA, Baronio F, Guerrini R, Mooney SD, Morrone A. Medium-Chain Acyl-CoA Deficiency: Outlines from Newborn Screening, In Silico Predictions, and Molecular Studies. ScientificWorld Journal. 2013 Oct 31;2013:625824. doi: 10.1155/2013/625824. 16. Balsamo A, Baronio F, Berra M, Bertelloni S, D'Alberton F, Marrocco G, Vallasciani S. Comment on "complete androgen insensitivity syndrome: optimizing diagnosis and management". Case Rep Obstet Gynecol. 2014;2014:285715
• 17. Chien YH, Abdenur JE, Baronio F, Bannick AA, Corrales F, Couce M, Donner MG, Ficicioglu C, Freehauf C, Frithiof D, Gotway G, Hirabayashi K, Hofstede F, Hoganson G, Hwu WL, James P, Kim S, Korman SH, Lachmann R, Levy H, Lindner M, Lykopoulou L, Mayatepek E, Muntau A, Okano Y, Raymond K, Rubio-Gozalbo E, Scholl-Bürgi S, Schulze A, Singh R, Stabler S, Stuy M, Thomas J, Wagner C, Wilson WG, Wortmann S, Yamamoto S, Pao M, Blom HJ. Mudd's disease (MAT I/III deficiency): a survey of data for MAT1A homozygotes and compound heterozygotes. Orphanet J Rare Dis. 2015 Aug 20;10:99. 18.Bozzola M, Gertosio C, Gnoli M, Baronio F, Pedrini E, Meazza C, Sangiorgi L. Hereditary multiple exostoses and solitary osteochondroma associated with growth hormone deficiency: to treat or not to treat? Ital J Pediatr. 2015 Aug 4;41:53 19. Tonin R, Caciotti A, Funghini S, Pasquini E, Mooney SD, Cai B, Proncopio E, Donati MA, Baronio F, Bettocchi I, Cassio A, Biasucci G, Bordugo A, la Marca G, Guerrini R, Morrone A. Clinical relevance of short-chain acyl-CoA dehydrogenase(SCAD) deficiency: Exploring the role of new variants including the first SCAD-disease-causing allele carrying a synonymous mutation. BBA Clin. 2016 Mar 10;5:114-9.
• 20. Baronio F, Mazzanti L, Girtler Y, Tamburrino F, Fazzi A, Lupi F, Longhi S, Radetti G. The Influence of Growth Hormone Treatment on Glucose Homeostasis in GrowthHormone-Deficient Children: A Six-Year Follow-Up Study. Horm Res Paediatr. 2016 Sep 6;86(3):196-200 21. Zaniew M, Bökenkamp A, Ko³buc M, La Scola C, Baronio F, Niemirska A, Szczepañska M, Bürger J, La Manna A, Miklaszewska M, Rogowska-Kalisz A, Gellermann J, Zampetoglou A, Wasilewska A, Roszak M, Moczko J, Krzemieñ A, Runowski D, Siteñ G, Za³uska-Leniewska I, Fonduli P, Zurrida F, Paglialonga F, Gucev Z, Paripovic D, Rus R, Said-Conti V, Sartz L, Chung WY, Park SJ, Lee JW, Park YH, Ahn YH, Sikora P, Stefanidis CJ, Tasic V, Konrad M, Anglani F, Addis M, Cheong HI, Ludwig M, Bockenhauer D. Long-term renal outcome in children with OCRL mutations: retrospective analysis of a large international cohort. Nephrol Dial Transplant. 2016 Oct 5. 22. Baronio F, Mazzanti L, Girtler Y, Tamburrino F, Lupi F, Longhi S, Fanolla A, Radetti G. The influence of GH treatment on glucose homeostasis in girls with Turner Syndrome: a 7 years study. J Clin Endocrinol Metab. J Clin Endocrinol Metab. 2017 Mar 1;102(3):878-883.
• 23. Ortolano R, Baronio F, Masetti R, Prete A, Cassio A, Pession A. Letter to the Editors: Concerning "Divergent clinical outcomes of alphaglucosidase enzyme replacement therapy in two siblings with infantile-onset Pompe disease treated in the symptomatic or pre-symptomatic state" by Takashi M et al. Mol Genet Page 5 - Curriculum vitae of Federico Baronio Metab Rep. 2017 Mar 7;11:1. 24. Fanelli F, Baronio F, Ortolano R, Mezzullo M, Cassio A, Pagotto U, Balsamo A.Normative Basal Values of Hormones and Proteins of Gonadal and Adrenal Functions from Birth to Adulthood. Sex Dev. 2018;12(1-3):50-94. doi: 10.1159/000486840. Epub 2018 Feb 14. 25. Rocca MS, Ortolano R, Menabò S, Baronio F, Cassio A, Russo G, Balsamo A, Ferlin A, Baldazzi L. Mutational and functional studies on NR5A1 gene in 46,XY disorders of sex development: identification of six novel loss of function mutations. Fertil Steril. 2018 Jun;109(6):1105-1113.
• 26. F. Emma, M. Cappa, F. Antoniazzi, M. L. Bianchi, I. Chiodini, C.Eller Vainicher, N. Di Iorgi, M. Maghnie, A. Cassio, A. Balsamo, F. Baronio, L. de Sanctis, D. Tessaris, G. I. Baroncelli, S. Mora, M. L.Brandi, G. Weber, A. D¿Ausilio and E. P. Lanati X-linked hypophosphatemic rickets: an Italian experts¿ opinion survey. Italian Journal of Pediatrics, 2019 in press https://doi.org/10.1186/s13052-019-0654-6
• 27. D'Addato S, Fogacci F, Cicero AFG, Palmisano S, Baronio F, Biagi C, Borghi C.Severe hypercholesterolaemia in a paediatric patient with congenital analbuminaemia Nutr Metab Cardiovasc Dis. 2019 Mar;29(3):316-317. 28. Baronio F, Righi B, Righetti F, Bettocchi I, Ortolano R, Faldella G, Rondelli R, Pession A, Cassio A. Carnitine longitudinal pattern in preterm infants <1800&#8201;g body weight: a case-control study. Pediatr Res. 2019 Jul 10. doi:10.1038/s41390-019-0497-2. [Epub ahead of print] 29. Baronio F, Ortolano R, Menabò S, Cassio A, Baldazzi L, Di Natale V, Tonti G,Vestrucci B, Balsamo A. 46,XX DSD due to Androgen Excess in Monogenic Disorders of Steroidogenesis: Genetic, Biochemical, and Clinical Features. Int J Mol Sci. 2019 Sep 17;20(18). pii: E4605. doi: 10.3390/ijms20184605. Review. 30. Pofi, R., Prete, A., Thornton-Jones, V., Bryce, J., Ali, S. R., Faisal Ahmed, S., Balsamo, A., Baronio, F., Cannuccia, A., Guven, A., Guran, T., Darendeliler, F., Higham, C., Bonfig, W., de Vries, L., Bachega, T., Miranda, M. C., Mendonca, B. B., Iotova, V., Korbonits, M.,Tomlinson, J. W. (2020). Plasma Renin Measurements are Unrelated to Mineralocorticoid Replacement Dose in Patients With Primary Adrenal Insufficiency. The Journal of clinical endocrinology and metabolism, 105(1), dgz055. https://doi.org/10.1210/clinem/dgz055 31. Caletti, M. T., Bettocchi, I., Baronio, F., Brodosi, L., Cataldi, S., Petroni, M. L., Cassio, A., & Marchesini, G. (2020). Maternal PKU: Defining phenylalanine tolerance and its variation during pregnancy, according to genetic background. Nutrition, metabolism, and cardiovascular diseases : NMCD, 30(6), 977¿983. https://doi.org/10.1016/j.numecd.2020.02.003 32. Wasniewska MG, Morabito LA, Baronio F, Einaudi S, Salerno M, Bizzarri C, Russo G, Chiarito M, Grandone A, Guazzarotti L, Spinuzza A, Corica D, Ortolano R, Balsamo A, Abrigo E, Baldini Ferroli B, Alibrandi A, Capalbo D, Aversa T, Faienza MF; Adrenal Diseases Working Group of the Italian Society for Pediatric Endocrinology and Diabetology. Growth Trajectory and Adult Height in Children with Nonclassical Congenital Adrenal Hyperplasia. Horm Res Paediatr. 2020;93(3):173-181. doi: 10.1159/000509548. Epub 2020 Aug 18. PMID: 32810858. 33. Capalbo D, Moracas C, Cappa M, Balsamo A, Maghnie M, Wasniewska MG, Greggio NA, Baronio F, Bizzarri C, Ferro G, Di Lascio A, Stancampiano MR, Azzolini S, Patti G, Longhi S, Valenzise M, Radetti G, Betterle C, Russo G, Salerno M. Primary Adrenal Insufficiency in childhood: data from a large nationwide cohort. J Clin Endocrinol Metab. 2020 Nov 28:dgaa881. doi: 10.1210/clinem/dgaa881. Epub ahead of print. PMID: 33247909. 34. Balsamo A, Baronio F, Ortolano R, Menabo S, Baldazzi L, Di Natale V, Vissani S, Cassio A. Congenital Adrenal Hyperplasias Presenting in the Newborn and Young Infant. Front Pediatr. 2020 Dec 22;8:593315. doi: 10.3389/fped.2020.593315. PMID: 33415088; PMCID: PMC7783414. 35. Corcioni B, Renzulli M, Marasco G, Baronio F, Gambineri A, Ricciardi D, Ortolano R, Farina D, Gaudiano C, Cassio A, Pagotto U, Golfieri R. Prevalence and ultrasound patterns of testicular adrenal rest tumors in adults with congenital adrenal hyperplasia. Transl Androl Urol. 2021 Feb;10(2):562-573. doi: 10.21037/tau-20-998. PMID: 33718059; PMCID: PMC7947447.
• 36. Lucas-Herald AK, Bryce J, Kyriakou A, Ljubicic ML, Arlt W, Audí L, Balsamo A, Baronio F, Bertelloni S, Bettendorf M, Brooke A, Claahsen-van der Grinten HL, Davies J, Hermann G, de Vries L, Hughes IA, Tadokoro-Cuccaro R, Darendeliler F, Poyrazoglu S, Ellaithi M, Evliyaoglu O, Fica S, Stejereanu L, Gawlik A, Globa E, Zelinska N, Guran T, Güven A, Hannema S, Hiort O, Holterhus PM, Iotova V, Mladenov V, Jain V, Sharma R, Jennane F, Johnston C, Guerra-Junior G, Konrad D, Gaisl O, Krone NP, Krone R, Lachlan K, Li D, Lichiardopol C, Lisá L, Markosyan RL, Mazen I, Mohnike K, Niedziela M, Nordenstrom A, Rey RA, Skae M, Tack LJ, Tomlinson JW, Weintrob N, Cools M, Ahmed SF. Gonadectomy In Conditions Affecting Sex Development - A Registry-Based Cohort Study. Eur J Endocrinol. 2021 Mar 1:EJE-20-1058.R3. doi: 10.1530/EJE-20-1058. Epub ahead of print. PMID: 33780351. 37. Brennenstuhl H, Nashawi M, Schröter J, Baronio F, Beedgen L, Gleich F, Jeltsch K, von Landenberg C, Martini S, Simon A, Thiel C, Tsiakas K, Opladen T, Kölker S, Hoffmann GF, Haas D; Unified Registry for Inherited Metabolic Disorders (U-IMD) Consortium and the European Registry for Hereditary Metabolic Disorders (MetabERN). Phenotypic diversity, disease progression, and pathogenicity of MVK missense variants in mevalonic aciduria. J Inherit Metab Dis. 2021 Jun 18. doi: 10.1002/jimd.12412. Epub ahead of print. PMID: 34145613. 38. Ibba A, Del Pistoia M, Balsamo A, Baronio F, Capalbo D, Russo G, DE Sanctis L, Bizzarri C. Differences of sex development in the newborn: from clinical scenario to molecular diagnosis. Minerva Pediatr (Torino). 2021 Jun 21. doi: 10.23736/S2724-5276.21.06512-5. Epub ahead of print. PMID: 34152117. 39. Stancampiano MR, Lucas-Herald AK, Bryce J, Russo G, Barera G, Balsamo A, Baronio F, Bertelloni S, Valiani M, Cools M, Tack LJW, Darendeliler F, Poyrazoglu S, Globa E, Grinspon R, Hannema SE, Hughes IA, Tadokoro-Cuccaro R, Thankamony A, Iotova V, Mladenov V, Konrad D, Mazen I, Niedziela M, Kolesinska Z, Nordenström A, Ahmed SF. Testosterone Therapy and Its Monitoring in Adolescent Boys with Hypogonadism: Results of an International Survey from the I-DSD Registry. Sex Dev. 2021;15(4):236-243. doi: 10.1159/000516784. Epub 2021 Jul 7. PMID: 34350903. 40. Assirelli V, Baronio F, Ortolano R, Maltoni G, Zucchini S, Di Natale V, Cassio A. Transient central precocious puberty: a new entity among the spectrum of precocious puberty? Ital J Pediatr. 2021 Oct 23;47(1):210. doi: 10.1186/s13052-021-01163-9. 41. Tack LJW, van der Straaten S, Riedl S, Springer A, Holterhus PM, Hornig NC, Kolesinska Z, Niedziela M, Baronio F, Balsamo A, Hannema SE, Nordenström A, Poyrazoglu S, Darendeliler FF, Grinspon R, Rey R, Aljuraibah F, Bryce J, Ahmed F, Tadokoro-Cuccaro R, Hughes I, Guaragna-Filho G, Maciel-Guerra AT, Guerra-Junior G, Cools M. Growth, puberty and testicular function in boys born small for gestational age with a nonspecific disorder of sex development. Clin Endocrinol (Oxf). 2021 Oct 20. doi: 10.1111/cen.14614. Epub ahead of print. PMID: 34668586.
• 42. Zucchini S, Di Iorgi N, Pozzobon G, Pedicelli S, Parpagnoli M, Driul D, Matarazzo P, Baronio F, Crocco M, Giudica G, Partenope C, Nardini B, Ubertini G, Menardi R, Guzzetti C, Iughetti L, Aversa T, Di Mase R, Cassio A, Cianfarani S, Maghnie M, Tuli G, Loche S, Bruzzi P, Wasniewska M, Salerno M, Rutigliano I, Iezzi ML, Cherubini V, Grandone A, Faienza M, Tumini S, Baldoli C, Consales A, Genitori L, Marras CE, MIlanaccio C, Mortini P, Vindigni M, Zenga F, Zucchelli M; Physiopathology of Growth Processes; Puberty Study Group of the Italian Society for Pediatric Endocrinology and Diabetology. Management of childhood-onset craniopharyngioma in Italy: A multicenter seven year follow-up study of 145 patients. J Clin Endocrinol Metab. 2021 Oct 29:dgab784. doi: 10.1210/clinem/dgab784. Epub ahead of print. PMID: 34718649. 43. Grünert SC, Schumann A, Baronio F, Tsiakas K, Murko S, Spiekerkoetter U, Santer R. Evidence for a Genotype-Phenotype Correlation in Patients with Pathogenic GLUT2 (SLC2A2) Variants. Genes (Basel). 2021 Nov 10;12(11):1785. doi: 10.3390/genes12111785. PMID: 34828390; PMCID: PMC8622088. 44. Baronio F, Zucchini S, Zulian F, Salerno M, Parini R, Cattoni A, Deodato F, Gaeta A, Bizzarri C, Gasperini S, Pession A. Proposal of an Algorithm to Early Detect Attenuated Type I Mucopolysaccharidosis (MPS Ia) among Children with Growth Abnormalities. Medicina (Kaunas). 2022 Jan 8;58(1):97. doi: 10.3390/medicina58010097. PMID: 35056405; PMCID: PMC8780542. 45. Baronio F, Conti F, Miniaci A, Carfagnini F, Di Natale V, Di Donato G, Testi M, Totaro C, De Fanti A, Boenzi S, Dionisi-Vici C, Esposito S, Pession A. Diagnosis, treatment, and follow-up of a case of Wolman disease with hemophagocytic lymphohistiocytosis. Mol Genet Metab Rep. 2021 Dec 20;30:100833. doi: 10.1016/j.ymgmr.2021.100833. PMID: 35242567; PMCID: PMC8856920. 46. Nowotny H, Neumann U, Tardy-Guidollet V, Ahmed SF, Baronio F, Battelino T, Bertherat J, Blankenstein O, Bonomi M, Bouvattier C, Brac de la Perrière A, Brucker S, Cappa M, Chanson P, Claahsen-van der Grinten HL, Colao A, Cools M, Davies JH, Dörr HG, Fenske WK, Ghigo E, Giordano R, Gravholt CH, Huebner A, Husebye ES, Igbokwe R, Juul A, Kiefer FW, Léger J, Menassa R, Meyer G, Neocleous V, Phylactou LA, Rohayem J, Russo G, Scaroni C, Touraine P, Unger N, Vojtková J, Yeste D, Lajic S, Reisch N. Prenatal dexamethasone treatment for classic 21-hydroxylase deficiency in Europe. Eur J Endocrinol. 2022 Mar 23;186(5):K17-K24. doi: 10.1530/EJE-21-0554. PMID: 35235536.